Package: 100 tabs (50mcg/tab)

Active Substance: Liothyronine Sodium

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Liothyronine, also known as T3, is a synthetic form of the thyroid hormone triiodothyronine. Produced by SP-Laboratories, Liothyronine is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. This medication has gained attention in the fitness and bodybuilding communities for its potent fat-burning effects. By boosting metabolism, Liothyronine helps users achieve a leaner physique. Understanding how Liothyronine works, its indications, and potential side effects is essential for anyone considering its use for medical or fitness purposes.


Liothyronine is primarily indicated for the treatment of hypothyroidism, a condition characterized by an underactive thyroid gland. Symptoms of hypothyroidism include fatigue, weight gain, cold intolerance, and depression. By supplementing the body’s natural thyroid hormone, Liothyronine helps alleviate these symptoms and restore normal metabolic function. In the context of fitness and bodybuilding, Liothyronine is used off-label for its ability to increase metabolism and promote fat loss. Athletes and bodybuilders often use it during cutting cycles to help shed excess body fat and enhance muscle definition.


Liothyronine is not suitable for everyone and has several contraindications. Individuals with untreated adrenal insufficiency or hyperthyroidism should not use this medication, as it can exacerbate these conditions. It is also contraindicated for those with acute myocardial infarction or uncorrected adrenal cortical insufficiency. Pregnant or breastfeeding women should use Liothyronine with caution and under the guidance of a healthcare provider, as thyroid hormone levels must be carefully managed during pregnancy and lactation. People with known hypersensitivity to Liothyronine or any of its components should avoid this medication.


Liothyronine is administered orally, typically in tablet form. The dosage and duration of use depend on the individual’s condition and treatment goals. For hypothyroidism, the usual starting dose is 25 micrograms per day, which may be gradually increased based on the patient’s response and thyroid hormone levels. In the context of fat loss, bodybuilders often start with a lower dose, such as 12.5 micrograms per day, and gradually increase it to 25-50 micrograms per day, depending on tolerance and desired results. It is crucial to follow the prescribed dosage and administration schedule to achieve the desired effect while minimizing potential side effects.

Medical Action

Liothyronine works by mimicking the action of the natural thyroid hormone triiodothyronine (T3). It binds to thyroid hormone receptors in various tissues, stimulating metabolic processes and increasing the basal metabolic rate. This leads to enhanced calorie burning and energy production, even at rest. In individuals with hypothyroidism, Liothyronine helps restore normal thyroid function, alleviating symptoms such as fatigue and weight gain. For bodybuilders and athletes, the increased metabolic rate induced by Liothyronine promotes fat loss and muscle definition, making it a valuable tool for achieving a lean physique.


Before starting Liothyronine, a thorough medical evaluation is necessary. Regular monitoring of thyroid hormone levels is recommended to ensure the medication is effective and to adjust the dosage if needed. Individuals should inform their healthcare provider about any other medications they are taking, as Liothyronine can interact with certain drugs, particularly anticoagulants, insulin, and oral hypoglycemic agents. It is also essential to be aware of the signs of overdosage, such as rapid weight loss, increased heart rate, and nervousness, and to report any symptoms to a healthcare provider immediately.

Side Effects

Like any medication, Liothyronine can cause side effects. Common side effects include headache, sweating, increased appetite, and nervousness. These symptoms are usually mild and tend to diminish with continued use. Some individuals may experience more severe side effects, such as rapid or irregular heartbeat, chest pain, or shortness of breath. In rare cases, long-term use of high doses of Liothyronine can lead to bone loss and decreased bone density. If any severe or persistent side effects occur, it is important to seek medical attention immediately. Regular follow-ups with a healthcare provider are crucial to monitor for any adverse effects and to adjust the treatment plan as needed.


An overdose of Liothyronine can lead to serious health complications. Symptoms of overdose may include severe weight loss, increased heart rate, chest pain, nervousness, and tremors. In extreme cases, it can cause cardiac arrhythmias, heart failure, or thyroid storm, a life-threatening condition characterized by extremely high levels of thyroid hormone. If an overdose is suspected, it is crucial to seek emergency medical help immediately. Treatment typically involves supportive care, including monitoring of vital signs and administration of medications to counteract the effects of the overdose. Adhering strictly to the prescribed dosage and administration guidelines can prevent the risk of overdose.


Liothyronine (T3) from SP-Laboratories is a potent oral medication that plays a vital role in the treatment of hypothyroidism and the management of body fat in fitness and bodybuilding. Its ability to increase metabolic rate and promote fat loss makes it an invaluable tool for achieving therapeutic and performance goals. However, it is essential to use Liothyronine responsibly and under the supervision of a healthcare professional. Understanding the indications, contraindications, proper administration, and potential side effects can help users maximize the benefits while minimizing risks. Always consult with a healthcare provider before starting any new medication to ensure it is appropriate for your individual health needs.


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