Package: 30 tabs (20mg/tab)

Active Substance: Tamoxifen Citrate

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Nolvaxyl, also known as Tamoxifen Citrate, is an oral medication produced by Kalpa Pharmaceuticals. It is primarily indicated for the treatment and prevention of breast cancer, particularly in patients with estrogen receptor-positive (ER+) breast cancer. Tamoxifen Citrate works by binding to estrogen receptors, thereby blocking the effects of estrogen in breast tissue. This makes it a crucial medication for reducing the risk of breast cancer recurrence. Additionally, Nolvaxyl has gained popularity in the bodybuilding community for its role in Post Cycle Therapy (PCT). PCT is essential after anabolic steroid cycles to restore the body’s natural hormone balance and prevent estrogen-related side effects.


Despite its effectiveness, Nolvaxyl is not suitable for everyone. The main contra-indications include:

  1. Pregnancy and Breastfeeding: Tamoxifen can harm an unborn baby and should not be used by women who are pregnant or breastfeeding.
  2. History of Blood Clots: Individuals with a history of deep vein thrombosis or pulmonary embolism should avoid using this medication.
  3. Allergy to Tamoxifen: Those who have a known allergy to Tamoxifen or any of its components should not use Nolvaxyl.
  4. Severe Liver Disease: Tamoxifen is metabolized by the liver, and severe liver impairment can lead to serious complications.


The administration of Nolvaxyl for PCT involves careful dosing and timing to maximize its benefits and minimize potential risks:

  1. Dosage: For PCT purposes, bodybuilders typically take 20 mg to 40 mg of Tamoxifen daily. The exact dosage depends on the severity of the steroid cycle and individual response.
  2. Timing: Tamoxifen is often introduced towards the end of an anabolic steroid cycle or immediately after to manage estrogen levels effectively.
  3. Cycle Length: The duration of Tamoxifen use in PCT can vary but generally lasts for 4 to 6 weeks. Prolonged use beyond this period can lead to excessive estrogen suppression.
  4. Monitoring: Regular monitoring of hormone levels is recommended to adjust the dosage accordingly and ensure optimal outcomes.

Medical Action

Nolvaxyl works by blocking estrogen receptors, particularly in breast tissue. This mechanism of action is beneficial for both cancer treatment and PCT:

  1. Estrogen Blockade: By binding to estrogen receptors, Tamoxifen prevents estrogen from exerting its effects, reducing the risk of estrogen-dependent breast cancer growth.
  2. Hormone Balance: In the context of PCT, reducing estrogen levels helps restore the balance between testosterone and estrogen, facilitating the recovery of natural testosterone production.
  3. Anti-Catabolic Effect: Maintaining higher testosterone levels while reducing estrogen can prevent muscle loss, which is crucial during the PCT phase.


Using Nolvaxyl requires adherence to several precautions to ensure safe and effective use:

  1. Hormone Levels: Regular blood tests to monitor hormone levels, including estrogen and testosterone, are essential to adjust the dosage and avoid over-suppression of estrogen.
  2. Liver Health: Since Tamoxifen is processed by the liver, users with pre-existing liver conditions should use this drug cautiously and under medical supervision.
  3. Blood Clots: Tamoxifen can increase the risk of blood clots. Individuals with a history of blood clotting disorders should be particularly cautious.
  4. Vision Changes: Rarely, Tamoxifen can cause vision disturbances. Any changes in vision should be reported to a healthcare provider immediately.
  5. Interactions: Tamoxifen can interact with other medications, including hormone replacement therapies and certain supplements. Consulting a healthcare provider before combining it with other treatments is advised.

Side Effects

Like any medication, Nolvaxyl can cause side effects. These can range from mild to severe:

Common Side Effects

  1. Hot Flashes: A common side effect due to hormonal changes.
  2. Nausea: Mild nausea or stomach discomfort is reported by some users.
  3. Fatigue: Tamoxifen can cause feelings of tiredness or weakness.
  4. Headaches: Frequent headaches may occur, especially during the initial stages of use.
  5. Weight Gain: Some users may experience weight gain due to fluid retention.

Severe Side Effects

  1. Blood Clots: Tamoxifen can increase the risk of deep vein thrombosis and pulmonary embolism.
  2. Endometrial Changes: Long-term use can increase the risk of endometrial cancer.
  3. Liver Dysfunction: Though rare, severe liver issues can occur, necessitating regular liver function tests.
  4. Vision Changes: Tamoxifen can cause vision disturbances, including cataracts and retinopathy.
  5. Mood Changes: Some users may experience mood swings, depression, or anxiety.


In the case of an overdose, immediate medical attention is necessary. Symptoms of Tamoxifen overdose may include:

  1. Severe Nausea and Vomiting: Excessive intake can cause severe gastrointestinal distress.
  2. Dizziness and Fainting: Overdosage can lead to extreme dizziness and potential fainting spells.
  3. Breathing Difficulties: Respiratory issues may arise in severe cases.
  4. Blood Clots: Increased risk of thrombosis.

Treatment for overdosage is supportive and symptomatic, focusing on stabilizing the patient and addressing specific symptoms. There is no specific antidote for Tamoxifen overdose.


Nolvaxyl from Kalpa Pharmaceuticals, known as Tamoxifen Citrate, is a potent selective estrogen receptor modulator (SERM) with significant applications in both medical and bodybuilding communities. While it is primarily used for treating and preventing hormonally-responsive breast cancer, its ability to block estrogen receptors has made it a valuable tool in Post Cycle Therapy for bodybuilders. By reducing estrogen, Tamoxifen helps prevent estrogen-related side effects and supports the recovery of natural testosterone production after anabolic steroid cycles.

However, the use of Nolvaxyl requires careful consideration of its contra-indications, potential side effects, and necessary precautions. Proper administration, including dosage management and monitoring hormone levels, is crucial to maximizing its benefits and minimizing risks. Regular health check-ups, a balanced diet, and a well-structured PCT plan can help users safely harness the advantages of Nolvaxyl while mitigating associated risks. By adhering to these guidelines, individuals can effectively use Tamoxifen to support their bodybuilding goals and maintain overall health and well-being.


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