Package: 1 vial (100mg/ml 10ml)

Active Substance: Drostanolone Propionate

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Mastaplex 100, also known as Drostanolone Propionate, is a widely-used injectable anabolic steroid produced by AxioLab. Known for its potent effects in enhancing muscle definition and hardness, Mastaplex 100 is a favorite among bodybuilders and athletes looking to improve their physical appearance and performance. In this guide, we will cover the indications, contra-indications, administration, medical action, precautions, side effects, overdosage, and conclude with its overall efficacy.


Mastaplex 100 is primarily indicated for individuals seeking to enhance their muscle definition, strength, and overall physical performance. It is especially popular during cutting cycles when the goal is to reduce body fat while preserving lean muscle mass. Medically, Drostanolone Propionate has been used in the treatment of breast cancer in postmenopausal women due to its anti-estrogenic properties. However, its primary use today is in the realm of bodybuilding and athletic performance enhancement.


Despite its benefits, Mastaplex 100 is not suitable for everyone. Here are the primary contra-indications:

  1. Pregnancy and Breastfeeding: Mastaplex 100 should not be used by women who are pregnant or breastfeeding, as it can cause harm to the fetus or infant.
  2. Prostate Cancer: Men with known or suspected prostate cancer should avoid this drug due to its androgenic effects.
  3. Breast Cancer: Women with certain types of breast cancer should not use Mastaplex 100 because of its androgenic properties.
  4. Severe Liver Disease: Individuals with significant liver impairment should refrain from using Mastaplex 100 due to potential liver strain.
  5. Cardiovascular Issues: Those with severe heart disease or high blood pressure should avoid using this steroid, as it can exacerbate these conditions.
  6. Allergic Reactions: Anyone with a known allergy to Drostanolone or any of its components should not use Mastaplex 100.


Mastaplex 100 is administered via intramuscular injection. The typical dosage for men ranges from 300 mg to 500 mg per week, depending on the user’s experience, goals, and tolerance. Beginners are advised to start with a lower dosage to assess their tolerance and minimize the risk of side effects. More experienced users may opt for higher dosages, but it is crucial to avoid excessive amounts to prevent severe adverse effects.

For women, the use of Mastaplex 100 is generally not recommended due to the high risk of virilization symptoms. However, if used, a very low dosage of 50 mg to 100 mg per week is recommended to minimize the risk. Mastaplex 100 is usually taken in cycles lasting from 6 to 8 weeks. Prolonged use beyond this period increases the risk of adverse effects and complications. The injections should be administered deep into the muscle, typically the glutes or thighs, using sterile techniques to prevent infection.

Medical Action

Mastaplex 100 works by binding to androgen receptors, which helps to increase protein synthesis and nitrogen retention in the muscles. This anabolic process leads to enhanced muscle growth, increased strength, and improved muscle hardness. Drostanolone Propionate is particularly effective at reducing body fat and enhancing muscle definition, making it a popular choice during cutting cycles.

In addition to its anabolic effects, Mastaplex 100 has anti-estrogenic properties, which help to prevent estrogen-related side effects such as water retention and gynecomastia. This makes it an ideal choice for bodybuilders looking to achieve a lean, dry, and vascular appearance. The drug’s short half-life requires frequent injections to maintain stable blood levels, ensuring consistent results throughout the cycle.


Using Mastaplex 100 requires certain precautions to ensure safety and effectiveness:

  1. Regular Monitoring: Regular blood tests to monitor liver function, kidney function, and cholesterol levels are recommended during a cycle to detect any adverse effects early.
  2. Cardiovascular Health: Monitoring blood pressure and cardiovascular health is crucial, as Mastaplex 100 can impact heart health.
  3. Diet and Hydration: A proper diet rich in protein and adequate hydration are essential to support muscle growth and overall health.
  4. Post Cycle Therapy (PCT): Implementing a PCT plan after completing a Mastaplex 100 cycle is essential to restore natural hormone production and minimize the risk of side effects.

Side Effects

Mastaplex 100 can cause a range of side effects, some of which can be significant:

  1. Androgenic Effects: Androgenic side effects can include acne, hair loss, and increased body hair growth. Women may experience virilization symptoms such as deepening of the voice, menstrual irregularities, and clitoral enlargement.
  2. Cardiovascular Issues: Mastaplex 100 can negatively impact cholesterol levels, increasing the risk of cardiovascular problems. It can reduce HDL (good) cholesterol and increase LDL (bad) cholesterol.
  3. Liver Strain: Although less hepatotoxic than oral steroids, prolonged use can still strain the liver. Regular liver function tests are recommended.
  4. Hormonal Imbalance: The drug can suppress natural testosterone production, leading to hormonal imbalances and potential infertility. Post Cycle Therapy (PCT) is crucial to restore natural hormone levels.


An overdose of Mastaplex 100 can be dangerous and requires immediate medical attention. Symptoms of overdose may include severe nausea, vomiting, jaundice (yellowing of the skin or eyes), dark urine, extreme fatigue, and severe hormonal imbalances. There is no specific antidote for testosterone overdose, and treatment is supportive, focusing on managing symptoms and preventing complications. In severe cases, hospitalization may be necessary.


Mastaplex 100, or Drostanolone Propionate, from AxioLab is a powerful injectable anabolic steroid used primarily to enhance muscle definition, strength, and overall physical performance. Its anti-estrogenic properties make it an ideal choice for cutting cycles, helping users achieve a lean, dry, and vascular appearance without significant water retention.

To use Mastaplex 100 safely and effectively, it is crucial to follow recommended dosages, implement proper precautions, and monitor health closely. Regular blood tests, cardiovascular health checks, and a well-planned Post Cycle Therapy (PCT) regimen are essential components of responsible Mastaplex 100 use. By adhering to these guidelines, users can achieve impressive muscle definition and enhanced physical performance while minimizing the risk of adverse effects and ensuring overall health and well-being.

Effect on Muscle Mass During Steroid Cycle

When used during a steroid cycle, Mastaplex 100 can significantly contribute to muscle mass and definition. It is especially effective during cutting phases when the goal is to reduce body fat while preserving lean muscle mass. The drug’s anabolic properties enhance protein synthesis and nitrogen retention, leading to increased muscle hardness and density.

Mastaplex 100’s ability to prevent estrogen-related side effects such as water retention and gynecomastia further enhances its effectiveness during cutting cycles. Users can achieve a lean, dry, and vascular appearance, which is highly desirable in competitive bodybuilding and athletic performance. Additionally, the drug’s short half-life ensures that users can maintain stable blood levels and consistent results throughout the cycle.

In summary, Mastaplex 100 from AxioLab is a versatile and effective injectable anabolic steroid that can help users achieve their muscle-building and definition goals. Its unique properties make it a valuable addition to cutting cycles, providing significant muscle hardness and improved physical performance with relatively mild side effects when used responsibly.


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