Package: 100 tabs (2.5mg/tab)

Active Substance: Letrozole

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Femara, also known as Letrozole, is an oral medication produced by Dragon Pharma. It is primarily used to treat hormone receptor-positive breast cancer in postmenopausal women. However, its effectiveness in reducing estrogen levels has made it a popular choice for Post Cycle Therapy (PCT) among bodybuilders and athletes. This guide covers all aspects of Femara, including its indications, contraindications, administration, medical action, precautions, side effects, overdosage, and conclusion.


Femara (Letrozole) is primarily indicated for:

  • Breast Cancer Treatment: It is used to treat hormone receptor-positive breast cancer in postmenopausal women. Letrozole helps reduce estrogen levels, slowing the growth of certain types of breast tumors that need estrogen to grow.
  • Post Cycle Therapy (PCT): Bodybuilders and athletes use Letrozole in PCT to combat estrogen-related side effects, such as gynecomastia, after a cycle of anabolic steroids. By lowering estrogen levels, Letrozole helps restore the body’s natural hormonal balance.


While Femara offers significant benefits, it is not suitable for everyone. Contraindications include:

  • Pre-menopausal Women: Letrozole is not indicated for women who have not gone through menopause.
  • Pregnancy and Breastfeeding: Femara is contraindicated in pregnant or breastfeeding women due to the risk of harm to the fetus or infant.
  • Severe Liver Disease: Individuals with severe liver impairment should avoid Letrozole, as it is metabolized in the liver and can exacerbate liver conditions.
  • Hypersensitivity: Those with a known allergy to Letrozole or any of its components should not use this medication.

It is crucial to consult with a healthcare provider to ensure Femara is safe and appropriate based on individual health conditions and medical history.


Femara is administered orally, typically in tablet form. The standard dosage for breast cancer treatment is 2.5 mg once daily, with or without food. It is essential to follow the prescribed dosage and administration guidelines provided by a healthcare provider.

For Post Cycle Therapy (PCT), the dosage may vary depending on individual needs and the specific steroid cycle completed. A common PCT regimen involves taking 0.5 mg to 2.5 mg of Letrozole daily or every other day for a duration of 4-6 weeks. Adjustments to the dosage and duration should be made based on individual response and under the guidance of a healthcare professional.

Medical Action

Femara (Letrozole) is an aromatase inhibitor that works by inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogens. This reduction in estrogen levels leads to several beneficial effects:

  • Breast Cancer Treatment: By lowering estrogen levels, Letrozole helps slow the growth of hormone receptor-positive breast cancer cells that require estrogen to proliferate.
  • Post Cycle Therapy (PCT): In PCT, Letrozole helps mitigate estrogen-related side effects, such as gynecomastia and water retention, that can occur after anabolic steroid use. By reducing estrogen levels, Letrozole aids in restoring the body’s natural hormonal balance and supports the recovery of endogenous testosterone production.

The effectiveness of Letrozole in lowering estrogen levels makes it a valuable tool in both medical and athletic contexts.


Before starting Femara, it is crucial to undergo a thorough medical evaluation. This includes a complete medical history and physical examination to assess liver function, cardiovascular health, and overall health status. Regular monitoring is necessary to track progress and detect any adverse effects.

Patients should inform their healthcare provider of any pre-existing medical conditions, allergies, or medications they are taking to prevent potential drug interactions and complications.

Maintaining a healthy lifestyle, including a balanced diet and regular exercise, is crucial when using Letrozole. Monitoring bone health is also important, as long-term use of aromatase inhibitors can lead to decreased bone density.

Side Effects

Like any potent medication, Femara can cause side effects. Common side effects include:

  • Hot Flashes: A common side effect due to the reduction in estrogen levels.
  • Joint Pain: Some users may experience joint or muscle pain.
  • Fatigue: Feeling tired or weak is a reported side effect.
  • Nausea: Some individuals may experience nausea or gastrointestinal discomfort.
  • Headaches: Headaches are a possible side effect of Letrozole.

Less common but more serious side effects include:

  • Osteoporosis: Long-term use of Letrozole can lead to decreased bone density and an increased risk of fractures.
  • Cardiovascular Issues: There is a potential risk of cardiovascular problems, such as hypertension or heart disease, with long-term use.
  • Liver Function: Letrozole can affect liver function, so regular monitoring is important.

If any severe side effects occur, it is crucial to seek medical attention immediately. Adjusting the dosage or discontinuing the use of Letrozole may be necessary to mitigate adverse effects.


An overdose of Femara can lead to severe health complications. Symptoms of overdose may include severe headache, dizziness, fainting, jaundice (yellowing of the skin or eyes), and abdominal pain. In extreme cases, an overdose can cause liver failure or heart attack.

If an overdose is suspected, it is essential to seek emergency medical assistance. Treatment typically involves supportive care and monitoring of vital signs. In some cases, medications may be administered to counteract the effects of excess Letrozole.


Femara, or Letrozole, from Dragon Pharma, is a potent oral aromatase inhibitor known for its ability to reduce estrogen levels. Its primary use in treating hormone receptor-positive breast cancer in postmenopausal women highlights its effectiveness in a medical context. Additionally, its role in Post Cycle Therapy (PCT) for bodybuilders and athletes demonstrates its versatility in promoting hormonal balance and mitigating estrogen-related side effects.

However, it is crucial to use Letrozole responsibly and under the guidance of a healthcare provider. Regular monitoring and adherence to recommended dosages help to minimize the risk of side effects and ensure optimal results. With proper use, Letrozole can be an effective solution for both medical treatments and athletic performance enhancement.

By understanding the indications, contraindications, administration, medical action, precautions, side effects, and potential for overdosage, users can make informed decisions about using Femara. This comprehensive approach ensures that the benefits are maximized while minimizing the risks associated with this potent medication.

Femara’s impressive ability to reduce estrogen levels and support hormone balance makes it a valuable tool for those looking to achieve their health and fitness goals. As with any potent drug, responsible use and thorough understanding of its effects are essential to achieving the best possible outcomes.


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