Package:1 vial (250mg/ml 10 ml)
Active Substance: 

Testosterone Propionate – 30mg;

Testosterone Phenylpropionate – 60mg;

Testosterone Isocaproate – 30mg;

Testosterone Decanoate – 100mg

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Sustandrol is a medication manufactured by Balkan Pharmaceuticals containing a mixture of testosterone esters as its active ingredients. It is commonly known as Sustanon, which is a blend of four different testosterone esters: testosterone propionate, testosterone phenylpropionate, testosterone isocaproate, and testosterone decanoate. This combination provides both fast-acting and long-lasting effects, making Sustandrol a popular choice for testosterone replacement therapy (TRT). Sustandrol is administered via intramuscular injection and is available by prescription only. This comprehensive guide will provide detailed information on Sustandrol, including its indications, contraindications, administration, medical action, precautions, side effects, and overdosage.

Indications for Use

Sustandrol is indicated for use in hormone replacement therapy in men with conditions associated with deficiency or absence of endogenous testosterone. Testosterone plays a crucial role in maintaining various bodily functions, including the development and maintenance of male secondary sexual characteristics, such as facial and body hair, deepening of the voice, and muscle growth. Testosterone deficiency can lead to symptoms such as fatigue, decreased libido, erectile dysfunction, depression, and decreased muscle mass. Sustandrol is also used in the treatment of delayed puberty, certain types of impotence, and in hormone therapy for transgender men to masculinize secondary sexual characteristics.


Sustandrol should not be used in patients with certain medical conditions or circumstances. Contraindications to the use of Sustandrol include:

  • Prostate cancer: Testosterone can stimulate the growth of prostate cancer cells and may worsen the condition. Sustandrol is contraindicated in patients with known or suspected prostate cancer.
  • Breast cancer in men: Testosterone can also stimulate the growth of breast tissue in men, exacerbating the condition in patients with breast cancer. Sustandrol should not be used in men with breast cancer.
  • Pregnancy and breastfeeding: Sustandrol is contraindicated in pregnant or breastfeeding women due to the potential for virilization of the fetus or newborn.
  • Hypersensitivity: Individuals with a known hypersensitivity to testosterone or any of its components should not use Sustandrol.
  • Severe hepatic or renal impairment: Sustandrol should be used with caution in patients with severe liver or kidney disease, as testosterone metabolism may be altered in these conditions.


Sustandrol is administered via intramuscular injection into the gluteal muscle. The dosage and frequency of administration should be determined by a healthcare professional based on individual patient needs and response to treatment. The usual starting dose of Sustandrol for hormone replacement therapy is 250 mg injected every 2 to 4 weeks. In some cases, higher doses may be required, especially in individuals with severe testosterone deficiency or certain medical conditions. Sustandrol is available in vials containing a mixture of testosterone esters, typically in the following proportions: testosterone propionate 30 mg, testosterone phenylpropionate 60 mg, testosterone isocaproate 60 mg, and testosterone decanoate 100 mg per ml.

Medical Action

The combination of testosterone esters in Sustandrol provides both fast-acting and long-lasting effects. Testosterone propionate and testosterone phenylpropionate are rapidly absorbed and exert their effects within a few days, while testosterone isocaproate and testosterone decanoate have a slower onset of action but provide sustained testosterone levels over a longer period. Testosterone binds to androgen receptors in various tissues, where it exerts its effects. In addition to its role in sexual development, testosterone also has anabolic effects, promoting the growth of muscle tissue and bone mass. It also enhances libido, mood, and overall sense of well-being.


Before initiating treatment with Sustandrol, patients should undergo a thorough medical evaluation, including assessment of prostate health and hematocrit levels. Regular monitoring of prostate-specific antigen (PSA), hematocrit, lipid profile, and liver function tests is recommended during therapy. Use with caution in individuals with cardiovascular disease, diabetes, epilepsy, migraine, or sleep apnea, as testosterone therapy may exacerbate these conditions. Sustandrol should be used with caution in elderly patients, as they may be more sensitive to its effects.

Side Effects

Sustandrol may cause side effects in some individuals. Common side effects of Sustandrol include:

  • Acne: Testosterone can stimulate the sebaceous glands, leading to an increase in acne.
  • Oily skin: Testosterone may increase the production of sebum, resulting in oily skin.
  • Fluid retention: Testosterone can cause sodium and water retention, leading to edema.
  • Gynecomastia: Testosterone can be converted to estrogen in the body, leading to the development of breast tissue in men.
  • Male pattern baldness: Testosterone can accelerate hair loss in individuals predisposed to male pattern baldness.
  • Mood changes: Testosterone therapy may cause mood swings, irritability, or aggression.
  • Liver toxicity: Testosterone may increase liver enzymes, indicating liver toxicity.
  • Alterations in lipid profile: Testosterone therapy may affect lipid metabolism, leading to changes in cholesterol levels.


In case of overdose, symptomatic and supportive treatment should be provided. Overdose may result in excessive androgenic effects such as virilization in women, suppression of spermatogenesis, and exacerbation of side effects mentioned above. Prompt medical attention is advised in case of suspected overdose. Treatment may include discontinuation of Sustandrol, supportive care, and monitoring of symptoms.


Sustandrol (Mixture of Testosterone Esters) is a medication used in hormone replacement therapy to treat conditions associated with low levels of testosterone in men. It is also used in the treatment of delayed puberty, certain types of impotence, and in hormone therapy for transgender men. Sustandrol is administered via intramuscular injection and is available by prescription only. Before starting Sustandrol therapy, patients should undergo a thorough medical evaluation to assess their suitability for treatment. Regular monitoring of prostate health, hematocrit levels, and liver function is recommended during therapy. Sustandrol may cause side effects in some individuals, including acne, fluid retention, gynecomastia, and mood changes. In case of overdose, prompt medical attention is advised.


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