Package: 100 tabs (1mg/tab)

Active Substance: Anastrozole

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Arimidex, also known as Anastrozole, is a potent oral medication produced by Dragon Pharma. This guide covers all aspects of Arimidex, including its indications, contraindications, administration, medical action, precautions, side effects, overdosage, and conclusion. Arimidex is especially noted for its effectiveness in combating gynecomastia, a condition characterized by the enlargement of male breast tissue.


Arimidex is primarily indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is used as an adjuvant therapy, meaning it is given after the primary treatment, such as surgery, to reduce the risk of cancer recurrence. Arimidex is also used in the treatment of advanced breast cancer in women whose disease has progressed after tamoxifen therapy.

In addition to its primary use in breast cancer treatment, Arimidex has gained popularity in the bodybuilding and fitness community for its ability to combat gynecomastia. Gynecomastia occurs when there is an imbalance between estrogen and testosterone levels in the body, leading to the development of breast tissue in men. By inhibiting the aromatase enzyme, which converts testosterone to estrogen, Arimidex helps to reduce estrogen levels and prevent or treat gynecomastia.


While Arimidex offers significant benefits, it is not suitable for everyone. Several contraindications should be considered before using this drug:

  • Pregnancy and Breastfeeding: Arimidex is contraindicated in women who are pregnant or breastfeeding due to the potential for harm to the fetus or infant.
  • Pre-menopausal Women: This medication is not intended for use in pre-menopausal women, as its effectiveness and safety in this group have not been established.
  • Severe Liver Disease: Individuals with severe liver dysfunction or liver disease should avoid using Arimidex, as it can exacerbate liver issues.
  • Allergy to Anastrozole or its Components: Those with a known allergy to Anastrozole or any of its components should not use this drug.

Patients with a history of osteoporosis or cardiovascular disease should use Arimidex with caution, as it can affect bone density and cholesterol levels.


Arimidex is administered orally in tablet form. The typical dosage for breast cancer treatment is one 1 mg tablet taken once daily. The treatment duration varies depending on the individual patient’s condition and response to therapy. It is usually taken for several years as part of a comprehensive breast cancer treatment plan.

For bodybuilding purposes, particularly for combating gynecomastia, the dosage may vary. A common dosage is 0.5 to 1 mg per day, although some users may take it every other day based on their needs and tolerance. It is important to note that higher dosages and prolonged use increase the risk of side effects.

Consistency in taking the medication at the same time each day is important to maintain stable blood levels of the drug. Patients should follow their healthcare provider’s instructions closely and not alter the dosage or duration of treatment without consultation.

Medical Action

Arimidex, or Anastrozole, is a non-steroidal aromatase inhibitor. Aromatase is an enzyme that converts androgens (like testosterone) into estrogens. By inhibiting this enzyme, Arimidex significantly reduces estrogen levels in the body. This action is particularly beneficial in treating hormone receptor-positive breast cancer, as estrogen can promote the growth of cancer cells.

In men, Arimidex’s ability to lower estrogen levels makes it effective in combating gynecomastia. Gynecomastia is often caused by an imbalance between estrogen and testosterone. By reducing estrogen levels, Arimidex helps to restore hormonal balance and reduce the development of breast tissue in men. This makes it a valuable tool for bodybuilders and athletes who may experience gynecomastia as a side effect of anabolic steroid use.

Additionally, lower estrogen levels can help reduce water retention and fat deposition, contributing to a leaner physique.


Before starting Arimidex, it is essential to undergo a thorough medical evaluation. This includes blood tests to assess liver function, cholesterol levels, bone density, and overall health status. Regular monitoring is necessary to track progress and detect any adverse effects.

Patients should inform their healthcare provider of any pre-existing medical conditions, allergies, or medications they are taking to prevent potential drug interactions and complications. Arimidex should be used cautiously in individuals with a history of osteoporosis, as it can reduce bone mineral density and increase the risk of fractures.

Maintaining a healthy lifestyle, including a balanced diet and regular exercise, is crucial when using Arimidex. Adequate calcium and vitamin D intake, along with weight-bearing exercises, can help to support bone health and minimize the risk of osteoporosis.

Side Effects

Like any potent medication, Arimidex can cause side effects. Common side effects include:

  • Hot Flashes: Many users experience hot flashes, which can be managed with lifestyle changes and medications if necessary.
  • Joint Pain: Arthralgia or joint pain is a common complaint, often affecting the hands, knees, and feet.
  • Fatigue: Some users report feeling tired or fatigued while taking Arimidex.
  • Mood Changes: Mood swings, anxiety, and depression have been reported in some individuals.
  • Nausea: Mild nausea and gastrointestinal discomfort can occur.

Less common but more serious side effects include:

  • Osteoporosis: Long-term use of Arimidex can lead to decreased bone mineral density and an increased risk of fractures.
  • Cardiovascular Issues: Changes in cholesterol levels (reduced HDL and increased LDL) can increase the risk of cardiovascular disease.
  • Liver Function: Elevated liver enzymes may occur, indicating liver stress.

If any severe side effects occur, it is crucial to seek medical attention immediately. Adjusting the dosage or discontinuing the use of Arimidex may be necessary to mitigate adverse effects.


An overdose of Arimidex can lead to severe health complications. Symptoms of overdose may include severe headache, dizziness, nausea, vomiting, and extreme fatigue. In extreme cases, an overdose can cause life-threatening conditions such as heart attack or stroke.

If an overdose is suspected, it is essential to seek emergency medical assistance. Treatment typically involves supportive care and monitoring of vital signs. In some cases, medications may be administered to counteract the effects of excess Anastrozole.


Arimidex from Dragon Pharma is a powerful oral medication that offers significant benefits for the treatment of hormone receptor-positive breast cancer in postmenopausal women and for combating gynecomastia in men. Its ability to inhibit the aromatase enzyme and reduce estrogen levels makes it a valuable tool in both medical and performance-enhancing contexts.

However, it is crucial to use Arimidex responsibly and under the guidance of a healthcare provider. Regular monitoring and adherence to recommended dosages help to minimize the risk of side effects and ensure optimal results. With proper use, Arimidex can be an effective solution for managing estrogen-related conditions and improving quality of life.

By understanding the indications, contraindications, administration, medical action, precautions, side effects, and potential for overdosage, users can make informed decisions about using Arimidex. This comprehensive approach ensures that the benefits are maximized while minimizing the risks associated with this potent medication.

Arimidex’s impressive ability to combat gynecomastia, support breast cancer treatment, and contribute to a leaner physique makes it a popular choice among men seeking to improve their health and physical capabilities. As with any potent drug, responsible use and thorough understanding of its effects are essential to achieving the best possible outcomes.


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