Package: 50 tabs (1mg/tab)

Active Substance: Anastrozole

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Anastrozol, marketed as Arimidex by Genetic Pharmaceuticals, is a potent oral medication widely used in the medical and bodybuilding communities. Primarily known for its role in managing estrogen levels, it is especially effective in Post Cycle Therapy (PCT) for those who have used anabolic steroids. This comprehensive guide will delve into various aspects of Anastrozol, including its indications, contraindications, administration, medical action, precautions, side effects, overdosage, and conclusion.


Anastrozol is indicated for:

  • Breast Cancer Treatment: Anastrozol is used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by lowering estrogen levels, which can help slow or reverse the growth of estrogen-sensitive tumors.
  • Post Cycle Therapy (PCT): In the bodybuilding community, Anastrozol is crucial for PCT. It helps restore natural testosterone production and prevents estrogen-related side effects after the use of anabolic steroids.

These indications highlight the versatility of Anastrozol in both clinical and non-clinical settings, making it an essential medication for various applications.


Anastrozol should not be used in the following situations:

  • Pregnancy and Breastfeeding: Anastrozol is contraindicated for women who are pregnant or breastfeeding due to potential harm to the baby.
  • Pre-menopausal Women: It is not recommended for women who have not yet gone through menopause.
  • Allergic Reactions: Individuals who have had an allergic reaction to Anastrozol or any of its ingredients should avoid this medication.
  • Severe Liver Disease: Patients with severe liver conditions should not use Anastrozol due to the risk of exacerbating liver dysfunction.
  • Severe Kidney Disease: Those with severe renal impairment should also avoid using this medication.

Consulting a healthcare provider before starting Anastrozol is crucial to determine if it is safe based on individual health conditions and medical history.


Anastrozol is administered orally in tablet form. The dosage and timing depend on the individual’s needs and the condition being treated.

  • Standard Dosage for Breast Cancer: The typical dose for breast cancer treatment is 1 mg per day. It is usually taken at the same time each day to maintain consistent blood levels.
  • Dosage for Post Cycle Therapy (PCT): In PCT, the dosage can vary. A common regimen is 0.5 mg to 1 mg every other day, adjusted based on the individual’s response and estrogen levels.
  • Cycle Duration: For breast cancer treatment, Anastrozol is often taken for several years. For PCT, the duration typically ranges from 2 to 4 weeks, depending on the cycle length and steroid use.

Following the recommended dosage and administration guidelines ensures the effectiveness and safety of Anastrozol.

Medical Action

Anastrozol, an aromatase inhibitor, works by inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogen. This leads to several beneficial effects:

  • Estrogen Reduction: By lowering estrogen levels, Anastrozol helps treat hormone receptor-positive breast cancer and prevents estrogen-related side effects in PCT.
  • Testosterone Restoration: In PCT, reducing estrogen levels helps stimulate the natural production of testosterone, aiding in the recovery of the body’s hormonal balance.
  • Prevention of Gynecomastia: Anastrozol prevents the development of gynecomastia (enlarged breast tissue in men), a common side effect of anabolic steroid use.

These actions make Anastrozol an effective medication for managing estrogen levels and supporting hormonal health.


Using Anastrozol requires certain precautions to ensure safety and effectiveness:

  • Health Monitoring: Individuals with underlying health conditions such as liver or kidney disease should be closely monitored while using Anastrozol.
  • Bone Health: Long-term use of Anastrozol can lead to bone thinning or osteoporosis. Regular bone density tests and adequate calcium and vitamin D intake are recommended.
  • Cholesterol Levels: Anastrozol can affect cholesterol levels. Monitoring cholesterol levels and maintaining a healthy diet are important.
  • Potential Interactions: Inform your healthcare provider about any other medications, supplements, or herbal products you are taking to avoid potential interactions.
  • Pregnancy Prevention: Women of childbearing age should use effective contraception while taking Anastrozol to prevent pregnancy.

Adhering to these precautions helps minimize risks and ensures the safe use of Anastrozol.

Side Effects

Anastrozol can cause a range of side effects, some common and others more severe. Common side effects include:

  • Hot Flashes: Many users experience hot flashes, a common symptom of reduced estrogen levels.
  • Joint Pain: Anastrozol can cause joint pain and stiffness, affecting daily activities.
  • Fatigue: Some individuals report feeling tired or fatigued while taking Anastrozol.
  • Nausea: Nausea and gastrointestinal discomfort are common, especially when starting treatment.

Less common but more serious side effects include:

  • Bone Thinning: Prolonged use can lead to osteoporosis or bone fractures.
  • Heart Problems: Anastrozol can increase the risk of cardiovascular issues, including heart disease and stroke.
  • Liver Dysfunction: Although rare, Anastrozol can cause liver problems, necessitating regular liver function tests.

It is essential to seek medical attention if severe side effects occur. Adjusting the dosage or discontinuing the use of Anastrozol may be necessary to mitigate adverse effects.


An overdose

of Anastrozol can lead to serious health complications. Symptoms of overdose may include:

  • Severe Nausea and Vomiting: Excessive intake of Anastrozol can cause intense nausea and vomiting.
  • Dizziness and Fainting: Overdose may result in severe dizziness or fainting due to a significant drop in estrogen levels.
  • Severe Joint Pain: Increased dosage can exacerbate joint pain and stiffness.
  • Liver and Kidney Issues: Anastrozol overdose can stress the liver and kidneys, potentially leading to dysfunction.

In the event of an overdose, it is crucial to seek emergency medical assistance immediately. Treatment typically involves supportive care and monitoring vital signs to manage symptoms and prevent further complications.


Anastrozol, also known as Arimidex from Genetic Pharmaceuticals, is a powerful and effective medication for managing estrogen levels, treating hormone receptor-positive breast cancer, and supporting Post Cycle Therapy (PCT) in the bodybuilding community. By understanding the indications, contraindications, administration, medical action, precautions, side effects, and overdosage information about Anastrozol, individuals can make informed decisions about its use.

In clinical settings, Anastrozol is a critical component in the fight against breast cancer, helping to slow or reverse tumor growth in postmenopausal women. For athletes and bodybuilders, it plays a crucial role in PCT, restoring natural testosterone production and preventing estrogen-related side effects after anabolic steroid use.

Always consult with a healthcare provider before starting Anastrozol to ensure it is the right choice based on personal health conditions and medical history. Using Anastrozol responsibly, adhering to medical advice, and monitoring health closely can maximize its benefits while minimizing potential risks.

With proper use and medical supervision, Anastrozol can be a valuable tool for achieving health and fitness goals, supporting hormonal balance, and enhancing overall well-being.


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